Technology

We have years of experience handling all aspects of phage therapy, from isolation and characterization to clinical applications.

What we do

Our core business

Fagoterapia LAB is developing an innovative approach to fight bacterial infections resistant to conventional antibiotics, based on the use of bacteriophages. Our five-steps process is able to deliver a personalised treatment in 7 to 10 days.

Bacterial Sampling

Bacterial Sampling

Bacteria DNA extraction and sequencing

Bacteria DNA extraction and sequencing

Optimized phage formulation identification

Optimized phage formulation identification

Phage scientific testing

Phage scientific testing

Formulation production and sending to hospitals

Formulation production and sending to hospitals

Bacterial Sampling

Bacteria DNA extraction and sequencing

Optimized phage formulation identification

Phage scientific testing

Formulation production and sending to hospitals

How we do it

Our assets

Fagoterapia LAB technology is based on three main assets that allow the production and delivery of an effective personalized therapy in extremely short time.

Phage bank

We hunt viruses

Fagoterapia LAB has collected during the years hundreds of bacteriophages active agains the most dangerous bacteria. Our laboratory offer both genomic and functional phage characterization service.

Our service includes:

  • Phage licensing from hundreds of isolates

  • Host identification

  • Phage identification and isolation

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Bioinformatics

Phage genomics has no secrets

During the years we designed protocols and tools for the bioinformatic analysis of phage genomes. Our proprietary algorithms allows to identify the phage host from the viral genome. Fagoterapia LAB has developed tools for the engineering of phages to increase breadth and optimise the killing function of phages.

Our service includes:

  • Phage sequencing, annotation and assembly

  • Phage host prediction and cocktail formulation

  • Phage engineering, gene knock-in/knock-out

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Clinical support

We care patients

Fagoterapia LAB is at the forefront of R&D of phage therapy in Italy. In 2023 the first italian patient affected by chronic hip-PJI was cured by our clinicians by means of customised phage therapy. During the years we built a solid network of collaborations with hospitals and research institute for the application of phage therapy.

We provide consultancy to hospitals for the application of phage therapy for clinical use, and therapy formulation.

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